Thoracic Surgery Oncology Group

Joining the Network

Join the North American thoracic surgery clinical trials network, aiming to improve the understanding of thoracic oncologic diseases and enhance the care of patients. Following the success of the first RFA in 2017, the network is expanding to involve more institutions in its clinical trial portfolio of studies involving thoracic malignancies.

Funding for all operational, correlative studies, institutional review board review, research study assistant support, and local administrative support will be the responsibility of each site in conjunction with the principal investigator (PI) of the proposal. The AATS will provide limited administrative support for TSOG .

The primary goal will be on rapid accrual and successful completion of thoracic surgeon lead clinical trials. While clinical trials can address many different problems, the focus of TSOG will be on phase I/II studies, window of opportunity trials with correlative analyses, intraoperative imaging studies, relevant registry studies, and multidisciplinary study designs.

Current Request for Application Process

Given the limited administrative support/resources and the need to accrue patients rapidly for trial completion, we anticipate no more than four to six sites will be activated in this upcoming RFA. The process involves submission of the application no later than the deadline. Following selection, chosen programs will convene for a “state-of-the-science” meeting which includes discussion of potential trials which will be selected as the index TSOG trials.

The application deadline has passed, but please check back in the future for the next RFA.

TSOG Site Selection Criteria

• High volume centers for thoracic oncologic procedures with an emphasis on lung, esophageal, and other thoracic malignancies
• Evidence of site-specific financial sustainability and existing infrastructure for completion of clinical trials
• Active participation of thoracic surgeons with expertise in oncologic clinical trial involvement and a history of robust accrual
• Institutional Redcap software license