The following is a collection of
congenital articles from the Journal of Thoracic and
Cardiovascular Surgery (JTCVS). To read the latest
issue and browse the Featured Video Library and other
journal highlights please visit www.jtcvs.org
An in-vitro analysis of the
PediMag™ and CentriMag™ for right-sided failing Fontan
Phillip M. Trusty, MS; Mike Tree, PhD;
Kevin Maher, MD; Timothy C. Slesnick, MD; Kirk R.
Kanter, MD; Ajit P. Yoganathan, PhD; Shriprasad R.
Deshpande3, MBBS, MS
PediMag and CentriMag right-sided
support reduced vena cava pressure and supported
cardiac output augmentation in an in vitro failing
Commentary: Fontan assist
device support: Road map to “stage 4” palliation
R. Broda, MD, Iki Adachi, MD
currently an unmet need for mechanical circulatory
support devices specifically focusing on the
right-sided hemodynamics to treat failing Fontan
CONGENITAL: SINGLE VENTRICLE
Determinants of Acute Events
Leading to Mortality After Shunt Procedure in
Tomislav Santro, MD, Yves d’Udekem, MD,
PhD, Diana Zannino, MS, Ben Hobbes, MD, Igor E.
Konstantinov, MD, PhD, Christian Brizard, MD, and
Johann Brink, MD
Over one-fifth of patients shunted
during univentricular palliation die before second
stage. The majority of these deaths are associated with
an acute event occurring early after surgery.
Commentary: Single ventricle
patients and shunts—ACute event is not pretty
Ronald K. Woods, MD, PhD, FACS, FAAP,
Viktor Hraska, MD, PhD
patients with single-ventricle circulation and a
systemic-to-pulmonary arterial shunt, an acute
event is associated with worse survival.
Commentary: The shunt and the precarious
physiology of the shunted circulation
Daniel Stromberg, MD, Carlos M. Mery,
multiprong approach is necessary to reduce the
complications and mortality in patients with a
single ventricle with systemic-to-pulmonary-artery shunts.
CONGENITAL: TETRALOGY OF FALLOT
Histopathology of the right
ventricular outflow tract and the relation to
hemodynamics in patients with repaired tetralogy of
Ujjwal Kumar Chowdhury, MCh, Diplomate
NB, Aandrei Jha, MCh, Ruma Ray, MD, FRCP, Mani
Kalaivani, MSc (Biostat), PhD, Suruchi Hasija, DM,
Lakshmi Kumari, MCh, Abhinavsingh Chauhan, MS
A presentation of intracardiac repair of
the tetralogy of Fallot using a trans-right atrial and
CONGENITAL: MECHANICAL CIRCULATORY SUPPORT
Computational Fluid Dynamics
Simulations of a Cavopulmonary Assist Device for Failing
W.C. Patrick Lin, MASc, Matthew G.
Doyle, PhD, S. Lucy Roche, MB ChB, Osami Honjo, MD,
PhD, Thomas L. Forbes, MD, Cristina H. Amon, ScD
Computational simulations of a novel
cavopulmonary assist strategy show potential as a
temporary option for treating patients with a failing
Commentary: The Fontan
paradox: A de Leval challenge
Tain-yen Hsia, MD, MSc
device that can lower systemic venous pressure by 5
mm Hg and increase pulmonary arterial pressure by 5
mm Hg might solve the Fontan paradox.
support for the subpulmonary circulation of Fontan
physiology—A step in the right direction
Christopher R. Broda, MD, Iki Adachi,
medical or surgical options available for patients
with failing Fontan circulation, innovative
solutions are needed to improve patient outcomes.
CONGENITAL: PERIOPERATIVE MANAGEMENT
High-dose heparin is associated
with higher bleeding and thrombosis rates in pediatric
patients following cardiac surgery
Carina N. Vorisek, MD, Lynn A. Sleeper,
ScD, Breanna Piekarski, MPH, Minmin Lu, MS, Jenna
Rogers, MPH, Olubunmi O. Oladunjoye, MBBS, Sitaram M.
Anticoagulation with high dose UFH is
associated with significantly higher bleeding and
thrombosis rates in children following cardiac surgery.
Thromboprophylaxis after congenital cardiac
surgery—Time for evidence-based guidelines
John P. Scott, MD
study identifies potential complications related to
high-dose heparin after pediatric cardiac surgery.
High-quality prospective studies are needed to
develop risk-stratified thromboprophylaxis