The following is a collection of featured congenital cardiac articles in press from the Journal of Thoracic and Cardiovascular Surgery (JTCVS). To read the latest issue, browse the feature video library and other journal highlights please visit www.jtcvs.org
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TRANSPOSITION OF THE GREAT ARTERIES
Outcomes of the arterial switch operation in patients with aortic arch obstruction
Tyson A. Fricke, MBBS, BMedSci, Samantha Donaldson, MD, BMedSci, James R. Schneider, MBChB, BS, MedSci, Samuel Menahem, MBBS, Yves d'Udekem, MD, PhD, Christian P. Brizard, MD, Igor E. Konstantinov, MD, PhD
Patients with dTGA or TBA with associated AAO represent a higher-risk subgroup undergoing the ASO with a higher operative mortality and reintervention rate, particularly for right-sided obstruction.
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Commentary: Transposition with aortic arch obstruction: the lesions switched?
Shyh-Jye Chen, MD, PhD, Shu-Chien Huang, MD, PhD
Arterial switch operations in patients with aortic arch obstruction require careful consideration for neopulmonary stenosis, residual aortic arch obstruction, and neoaortic regurgitation.
Commentary: Arterial switch and arch repair: one plus one doesn't always equal two
Chun Soo Park, MD, PhD
Technical simplification of arch repair using regular protocol renders complex transposition simpler, but more is needed to reduce the incidence of subsequent reintervention.
Longitudinal functional health status in young adults with repaired dextro-transposition of the great arteries: A Congenital Heart Surgeons' Society study
Anusha Jegatheeswaran, MD, PhD, Paul J. Devlin, MD, MSc, William M. DeCampli, MD, PhD, Karl F. Welke, MD, William G. Williams, MD, Eugene H. Blackstone, MD, Stephanie Fuller, MD, Marshall L. Jacobs, MD, Kathleen A. Mussatto, RN, PhD, Ronald K. Woods, MD, Brian W. McCrindle, MD, MPH
Adult patients with d-TGA, regardless of morphology or repair type, have primarily normal FHS. Symptom and heart condition management, education, and employment may be targets to improve poor FHS.
Commentary: There's more to life than just plain M&Ms
John N. Dentel, MD, Henry L. Walters III, MD
Outcomes are more than just morbidity and mortality; a comprehensive understanding of postoperative congenital heart disease patients' functional health status may improve their quality of life.
Commentary: Heroes of the arterial switch operation in the 1980s
Osman O. Al-Radi, MBBCh, MSs, FRCSC
Medical literature is written about survivors; this is written in honor of the true heroes of the arterial switch operation.
Commentary: Functional Health Status after repair of Transposition of the Great Arteries
Roosevelt Bryant III, MD
Young adult patients report normal functional health status after repair of transposition of the great arteries.
AORTIC VALVE
Maladaptive Remodeling of Pulmonary Artery Root Autografts After Ross Procedure: A Proteomic Study
Anna Chiarini, MS, Ilaria Dal Prà, MS, Giuseppe Faggian, MD, Ubaldo Armato, MD, Giovanni Battista Luciani, MD
Dilated autograft roots show a pattern of extracellular matrix, intercellular signaling, and cell adhesion changes distinct from both normal pulmonary artery and normal ascending aorta.
Commentary: Towards a biologic understanding of autograft dilatation in the Ross procedure: creating opportunities to rescue the neoaortic root
Michael Ibrahim, MA, MD, PhD, Audrey E. Spelde, MD, John G. Augoustides, MD, FASE, FAHA
The proteomic profiles of the dilated autograft may identify molecular predictors and isolate therapeutic targets for the failing neoaortic root. Future trials should explore these molecular signatures in the Ross procedure.
Commentary: Prediction of pulmonary root dilatation after Ross operation: the power of protein shake?
Igor E. Konstantinov, MD, PhD, FRACS, Federica Caldaroni, MD, Yaroslav Ivanov, MD
Proteomic studies may shed light on the causes of late autograft failure.
FEATURED VIDEO
Video Legend: Reop after Ross procedure
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FONTAN
Y-graft Modification to the Fontan Procedure: Increasingly Balanced Flow over Time
Phillip M. Trusty, PhD, Zhenglun Wei, PhD, Megan Sales, BS, Kirk R. Kanter, MD, Mark A. Fogel, MD, Ajit P. Yoganathan, PhD, Timothy C. Slesnick, MD
Y-graft hepatic flow distribution significantly improves over time, offering a potential advantage over extracardiac conduit options.
Commentary: Why Use the Y-Graft?
Ming-Sing Si, MD, Vikram Sood, MD, Edward Bove, MD
Use of the native pulmonary bifurcation can also be used to distribute flow and hepatic factor in the Fontan procedure.
Commentary: Why the Y-Graft?
Steven M. Schwartz, MD, MS, FRCPC, FAHA
Midterm outcome data on the Y-graft Fontan circulation are useful because of the novelty of the procedure, even if the scope of these data are limited.