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2008 Program & Abstracts
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Preliminary Program Outline
« 2008 Program Index
| TUESDAY MORNING, MAY 13, 2008 |
| 7:00 am |
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CARDIAC SURGERY FORUM SESSION
(5 minutes presentation, 7 minutes discussion)
Room 28 A-C, San Diego Convention Center
Moderators: Richard D. Weisel, Marc R. Moon
F1. Elimination of Moderate Ischemic MR does not Ameliorate Long-Term LV Remodeling
Kanji Matsusaki, Mio Noma, Aaron S. Blom, Thomas J. Eperjesi, Liam P. Ryan, Theodore Plappert, Martin G. St. John-Sutton, Joseph H. Gorman, Robert C. Gorman
Surgery, University of Pennsylvania, Philadelphia, PA, USA.
F2. Layered implantation of myoblast sheets attenuates cardiac remodeling of infarcted heart
Naosumi Sekiya1, Shigeru Miyagawa1, Goro Matsumiya1, Takaya Hoashi1, Tatsuya Shimizu2, Teruo Okano2, Yoshiki Sawa1
1. Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. 2. Tokyo Women’s Medical University, Tokyo, Japan.
F3. Newly developed tissue-engineered biodegradable material for reconstruction of vascular wall without cell seeding
Hiroaki Takahashi1, Mitsuhiro Saito2, Eiichirou Uchimura2, Koujirou Hirakawa3, Eiichi Kaku3, Yutaka Okita1, Yoshiki Sawa2
1. Department of Surgery, Division of Cardiovascular Surgery, Kobe University Graduate School of Medicine, Kobe, Japan. 2. Osaka University Graduate School of Medicine, Suita, Japan. 3. Senko Medical Ins. Co., Ltd., Tokyo, Japan.
F4. Atrophic changes occur in unloaded myocardium and may preclude functional improvement in a time dependent manner
Henriette L. Brinks1, Hendrik Tevaearai2, Christian Muehlfeld3, Daniela Kuklinski2, Thierry P. Carrel2, Marie-Noelle Giraud2
1. Cardiovascular Surgery, Charite University Hospital, Berlin, Berlin, Germany. 2. Department of Cardiac and Vascular Surgery, Inselspital University Hospital, Berne, Switzerland. 3. Institute of Anatomy, University of Berne, Berne, Switzerland.
F5. Acute Hyperglycemia Enhances Oxidative Stress During Reperfusion and Exacerbates Myocardial Infarction
Zequan Yang1, Victor E. Laubach1, Brent A. French2, Irving L. Kron1
1. Surgery, University of Virginia Health System, Charlottesville, VA, USA. 2. Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
F6. Development of Bioartificial Myocardium using Collagen Scaffold Functionalized with RGD Peptides
Olivier Schussler1, Walid Al Chare1, Mariana Louis-Tisserand1, Catherine Coirault2, Robert Michelot1, Malcolm Wood4, Didier Heude1, Alain Carpentier1, Juan Carlos Chachques1, Dan Salomon4, Yves Lecarpentier2,3
1. Laboratory of Biosurgery Pompidou Hospital, Paris, France. 2. INSERM U689 Paris VII University, Paris, France. 3. Le Kremlin Bicêtre, University Paris V and VII Paris, France 4. The Scripps Research Institut MEM 241, La Jolla, CA, USA.
F7. Mitral Valve Hemodynamics Following Repair of Acute Posterior Leaflet Prolapse: Quadrangular Resection vs. Triangular Resection vs. Neo-chordoplasty
Muralidhar Padala1, Laura R. Croft1, Scott Powell1, Vinod H. Thourani2, Ajit P. Yoganathan1, David H. Adams3
1. Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA. 2. Emory University, Atlanta, GA, USA. 3. Mt.Sinai School of Medicine, New York, NY, USA.
F8. Dynamic Fluid Shifts Induced by Fetal Cardiopulmonary Bypass
Pirooz Eghtesady1, Scott Baker2, Christopher Lam1, Hilshorst Jerri1, Ferguson Robert1, Lombardi John1
1. Cardiothoracic Surgery, Cincinnati Children’s Hospital, Cincinnati, OH, USA. 2. University of Cincinnati, Cincinnati, OH, USA.
F9. Toll-like Receptor 4 on Leukocytes is Necessary for Cardiomyocyte Hypoxia - Reoxygenation Injury
Heather-Marie P. Wilson, Denise J. Spring, Christine Rothnie, Erzsebet Toth, Edward D. Verrier
Surgery, University of Washington, Seattle, WA, USA.
F10. Development of Novel Synthetic Serine-Protease Inhibitors to Reduce Postoperative Blood Loss After Cardiac Surgery
Gábor Szabó1, Gabor Veres1, Tamás Radovits1, Matthias Karck1, Andreas van de Locht2
1. University of Heidelberg, Heidelberg, Germany. 2. Curacyte Discovery Ltd., Leipzig, Germany. |
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| TUESDAY MORNING, MAY 13, 2008 |
| 7:00 am |
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GENERAL THORACIC FORUM SESSION
(5 minutes presentation, 7 minutes discussion)
Room 25, San Diego Convention Center
Moderators: Michael A. Maddaus, Yolonda L. Colson
F11. Paclitaxel-Loaded Polymer Film Prevents Local Recurrence of Non-Small Cell Lung Cancer
Rong Liu1, Jesse Wolinsky2, Mark W. Grinstaff2, Yolonda L. Colson1
1. Brigham and Women’s Hospital, Boston, MA, USA. 2. Boston University, Boston, MA, USA.
F12. Targeting tumor angiogenesis in thoracic malignancies using MEK pharmacologic inhibitor: in vitro and in vivo analysis
Shailen Sehgal2, Wen-Shuz Yeow2, Mustafa Hussain2, Amy Loehfelm2, Joseph Blansfield2, Steven K. Libutti2, Craig Thomas2, Dao M. Nguyen1
1. Surgery, University of Miami, Miami, FL, USA. 2. National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
F13. Ambulatory Lung Assist Device Oxygenates and Removes Carbon Dioxide from Blood Across a Silicone-Coated Porous Membrane
David M. Hoganson1, Jennifer Anderson1, Brian Orrick2, Joseph P. Vacanti1
1. Massachusetts General Hospital, Boston, MA, USA. 2. Alito Therapeutics, Boston, MA, USA.
F14. Long Acting Oral Phophodiesterase Inhibition Preconditions Against Reperfusion Injury ln An Experimental Lung Transplantation Model
Eric S. Weiss1, Jason A. Williams1, William M. Baldwin2, William A. Baumgartner1, Hunter C. Champion3, Ashish S. Shah1
1. Cardiac Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. 2. Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. 3. Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
F15. Differential gene expression profiling of esophageal adenocarcinoma
Zane Hammoud, Sunil Badve, Qianqian Zhao, Lang Li, Karen Rieger, Kenneth Kesler
Indiana University School of Medicine, Indianapolis, IN, USA.
F16. Screening of Epidermal Growth Factor Receptor Gene Mutation in Non-small Cell Lung Cancer Using a New PCR-based Enzymatic Digestion Method
Young T. Kim2, Sun J. Park2, Joo-yeon Park2, Hyun C. Wi2, Chang H. Kang1, Sook W. Sung2, Joo H. Kim1
1. Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, South Korea. 2. Cancer Research Institite, Seoul National University, Seoul, South Korea.
F17. A novel JAK3 and Syk-Inhibitor, R348, for prevention of chronic airway allograft rejection
Jeffrey Velotta1, Vanessa Taylor2, Esteban Masuda2, Gary Park2, David Carroll2, Robert Robbins1, Sonja Schrepfer1
1. Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA. 2. Rigel Pharmaceuticals, South San Francisco, CA, USA.
F18. Association with Survival of the CXCL12-CXCR4 Chemokine Axis in Adenocarcinoma of the Lung
P. L. Wagner1, M. Vazquez2, J. Port1, P. Lee1, A. Saqi2, N. Altorki1
1. Cardiothoracic Surgery, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, USA. 2. Pathology, Weill Cornell Medical College, New York, NY, USA.
F19. Overexpression of Cyclooxygenase-2 is Associated with Chemoradiotherapy Resistance and Prognosis in Esophageal Squamous Cell Carcinoma Patients
Huang Weizhao2, Fu Jianhua1, Hu Yi1, Liu Mengzhong1, Yang Hong1, Zheng Bin1, Wang Geng1, Rong Tiehua1
1. Cancer Center, Sun Yat-Sen University, Guangzhou, China. 2. Cancer Center and ZhongShan Hospital, Sun Yat-Sen University, Zhongshan, China.
F20. Detergent-enzymatic bioengineered pig tracheal tubular matrices lack of immunogenicity and maintain their structural integrity when implanted heterotopically in an allo- and xenotransplantation model
Philipp Jungebluth1, Tetsuhiko Go1, Silvia Bellini2, Chiara Calore2, Luca Urbani2, Tatiana Chioato2, Michaela Turetta2, Adelaide M. Asnaghi3, Sara Mantero3, Maria T. Conconi2, Paolo Macchiarini1
1. Dept. of General Thoracic Surgery, Hospital Clinic, University of Barcelona, Barcelona, Spain. 2. Dept. of Pharmaceutical Sciences, University of Padua, Padua, Italy. 3. Dept. of Bioengineering, Politecnico di Milano, Milano, Italy. |
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| TUESDAY MORNING, MAY 13, 2008 |
| 9:00 am |
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PLENARY SCIENTIFIC SESSION
(8 minutes presentation, 12 minutes discussion)
Ballroom 20 A-C, San Diego Convention Center
Moderators: D. Craig Miller, Thoralf M. Sundt
29. Mid-Term Results of Endovascular treatment of acute and chronic aortic dissection: The Talent Thoracic Retrospective Registry (TTR)
Marek P. Ehrlich1, Stephan Kische2, Herve Rousseau3, Robin Heijmen4, Philippe Piquet5, Jean-Paul Beregi6, Christoph A. Nienaber2, Rossella Fattori7
1. Dept. Cardiothoracic Surgery, Univ. Hospital Vienna, Vienna, Austria. 2. Division of Cardiology, Univ. Hospital Rostock, Rostock, Germany. 3. Dept. of Radiology, Hopital de Rangueil, Toulouse, France. 4. Dept. Cardiothoracic Surgery, St. Antonius Hospital, Nieuwegein, Netherlands. 5. Hopital Sainte Marguerite, Marseille, France. 6. Hopital Cardiologique CHRU, Lille, France. 7. Cardiovascular Radiology, Univ. Hospital S. Orsola, Bologna, Italy.
30. Mechanical valves versus Ross procedure for aortic valve replacement in children: Propensity-adjusted comparison of long-term outcomes
Bahaaldin Alsoufi1, Cedric Manlhiot2, Brian McCrindle2, Mamdouh Al- Ahmadi1, Ahmed Sallehuddin1, Charles Canver1, Ziad Bulbul1, Mansoor Joufan1, Ghassan Siblini1, Zohair Al-Halees1, Bahaa Fadel1
1. King Faisal Heart Institute, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. 2. Hospital for Sick Children and University of Toronto, Toronto, ON, Canada.
31. How does the use of PTFE neochordae for posterior mitral valve prolapse (loop technique) compare with leaflet resection? Results of a prospective randomized trial
Volkmar Falk1, Markus Czesla1, Joerg Seeburger1, Thomas Kuntze1, Patrick Perrier2, Fitsum Lakev2, Joerg Ender1, Nicolas Doll1, Franka Nette1, Michael A. Borger1, Friedrich W. Mohr1
1. Heartcenter Leipzig, Leipzig, Germany. 2. Cardiovascular Center Bad Neustadt, Bad Neustadt, Germany. |
| 10:00 am |
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AWARD PRESENTATIONS
Ballroom 20 A-C, San Diego Convention Center |
| 10:15 am |
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INTERMISSION — VISIT EXHIBITS
Exhibit Hall |
| 11:00 am |
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32. Application of the Revised Lung Cancer Staging System (IASLC Staging Project) to a Cancer Center Population
Edmund S. Kassis1, Ara A. Vaporciyan1, Stephen G. Swisher1, Arlene M. Correa1, Neby Bekele2, Jeremy J. Erasmus3, Wayne L. Hofstetter1, Ritsuko Komaki4, Reza J. Mehran1, Cesar A. Moran5, Katherine M. Pisters6, David C. Rice1, Garrett L. Walsh1, Jack A. Roth1
1. The University of Texas MD Anderson Cancer Center, Department of Thoracic and Cardiovascular Surgery, Houston, TX, USA. 2. The University of Texas MD Anderson Cancer Center, Department of Bioinformatics & Computational Biology, Houston, TX, USA. 3. The University of Texas MD Anderson Cancer Center, Department of Radiology, Houston, TX, USA. 4. The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, Houston, TX, USA. 5. The University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, TX, USA. 6. The University of Texas MD Anderson Cancer Center, Department of Thoracic/Head and Neck Medical Oncology, Houston, TX, USA.
33. Selective Antegrade Cerebral Perfusion Via Right Axillary Artery Cannulation Reduces Morbidity and Mortality after Proximal Aortic Surgery
Michael E. Halkos, Faraz Kerendi, Richard Myung, Patrick D. Kilgo, John D. Puskas, Edward P. Chen
Emory University, Atlanta, GA, USA. |
| 11:40 am |
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ADDRESS BY HONORED SPEAKER
50 Years of Cardiothoracic Surgery through the Looking Glass and What the Future Holds
Marko I. Turina, M.D., University Hospital, Zurich Switzerland
Introduced By: D. Craig Miller |
| 12:20 pm |
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ADJOURN FOR LUNCH – VISIT EXHIBITS
Exhibit Hall, San Diego Convention Center
ACADEMIC LEADERSHIP LUNCHEON
San Diego Convention Center |
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| TUESDAY AFTERNOON, MAY 13, 2008 |
| 2:00 pm |
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SIMULTANEOUS SCIENTIFIC SESSION — ADULT CARDIAC SURGERY
(8 minutes presentation, 12 minutes discussion)
Ballroom 20 A-C, San Diego Convention Center
Moderators: Joseph F. Sabik, Andrew S. Wechsler
34. Equivalent Patencies of the Radial Artery, Right Internal Thoracic Artery and Saphenous Vein Beyond 5 Years: Surprising Results from the Radial Artery Patency and Clinical Outcomes Trial
Philip Hayward1, Mark Horrigan2, David L. Hare2, Ian Gordon3, George Matalanis2, Brian F. Buxton2
1. Cardiothoracic Surgery, Essex Cardiothoracic Centre, Basildon, United Kingdom. 2. Austin Hospital, Melbourne, VIC, Australia. 3. University of Melbourne Statistical Consulting Centre, Melbourne, VIC, Australia.
35. Efficacy of add mitral valve restrictive annuloplasty to CABG in patients with moderate ischemic mitral valve regurgitation
Khalil Fattouch, Francesco Guccione, Marco Muscarelli, Emiliano Navarra, Davide Calvaruso, Giuseppe Speziale, Giovanni Ruvolo
Cardiac Surgery, University of Palermo, Palermo, Italy.
Counterpoint: Alfredo Trento
Open Discussion
36. A Long Term Analysis of Percutaneous Fenestration and Stenting for Acute Type B Dissection with Malperfusion— Implications for Thoracic Aortic Endovascular Repair
Himanshu J. Patel, David M. Williams, Meir Meerkov, Narasimham L. Dasika, G. M. Deeb
University of Michigan Cardiovascular Center, Ann Arbor, MI, USA.
37. Hybrid endovascular aortic arch repair using branched endoprosthesis: The second generation ’branched’ open stent grafting technique
Kazuo Shimamura1, Toru Kuratani2, Yukitoshi Shirakawa2, Mugiho Takeuchi1, Hiroshi Takano3, Goro Mastumiya1, Yoshiki Sawa1
1. Department of cardiovascular surgery, Osaka university graduate school of medicine, Osaka, Japan. 2. Department of Advanced Cardiovascular Therapeutics,Osaka University Graduate School of medicine, Osaka, Japan. 3. Department of Cardiovascular Surgery, Osaka General Medical Center, Osaka, Japan. |
| 3:30 pm |
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INTERMISSION – VISIT EXHIBITS
Exhibit Hall, San Diego Convention Center |
| 4:05 pm |
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SIMULTANEOUS SCIENTIFIC SESSION
Ballroom 20 A-C, San Diego Convention Center
Moderators: Joseph F. Sabik, Andrew S. Wechsler
38. Cardiovascular Magnetic Resonance Assessment of Myocardial Scarring Predicts Recurrence of Functional Ischemic Mitral Regurgitation after Anuloplasty
Tomislav Mihaljevic, Michael Flynn, Ronan Curtin, Edward R. Nowicki, Jeevanantham Rajeswaran, Scott D. Flamm, Eugene H. Blackstone
Cleveland Clinic, Cleveland, OH, USA.
39. Prosthesis-Patient Mismatch is Irrelevant for Patients Greater than 70 Years of Age Undergoing Bioprosthetic Aortic Valve Replacement
Marc R. Moon, Jennifer S. Lawton, Nabil A. Munfakh, Nader Moazami, Kristen A. Aubuchon, Kelly A. Baker, Michael K. Pasque, Ralph J. Damiano
Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Counterpoint: Christopher M. Feindel
Open Discussion |
| 5:00 pm |
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EXECUTIVE SESSION (Members Only)
Ballroom 20 A-C, San Diego Convention Center |
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| TUESDAY AFTERNOON, MAY 13, 2008 |
| 2:00 p.m |
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SIMULTANEOUS SCIENTIFIC SESSION — GENERAL THORACIC SURGERY
(8 minutes presentation, 12 minutes discussion)
Room 25, San Diego Convention Center
Moderators: G. Alexander Patterson, Joe B. Putnam
40. Does reperfusion injury still cause significant mortality after lung transplantation?
Gorav Ailawadi, Christine L. Lau, Lynn M. Fedourk, Philip W. Smith, Courtney Kuhn, Benjamin D. Kozower, John A. Kern, Benjamin B. Peeler, Irving L. Kron, David R. Jones
TCV Surgery, University of Virginia, Charlottesville, VA, USA.
41. Does Endobronchial Ultrasonography have a place in the Thoracic Surgeon’s Armamentarium?
Sebastien Gilbert1, David O. Wilson2, Neil A. Christie1, James D. Luketich1, Matthew J. Schuchert1
1. Heart, Lung, and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. 2. The Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
42. Tailored Cricoplasty - An Improved Modification for Reconstruction in Subglottic Tracheal Stenosis
Moishe Liberman, Douglas J. Mathisen
Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA. |
| 3:00 pm |
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INTERMISSION — VISIT EXHIBITS
Exhibit Hall, San Diego Convention Center |
| 3:35 pm |
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SIMULTANEOUS SCIENTIFIC SESSION — GENERAL THORACIC SURGERY
Room 25, San Diego Convention Center
Moderators: G. Alexander Patterson, Joe B. Putnam
43. Analysis of surgical results leads to improved post-operative algorithms and fast-tracking of high risk patients after pulmonary resection
Ayesha Bryant, Robert J. Cerfolio
Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
44. VATS lobectomy versus thoracotomy for lung cancer. Results in 741 patients
Raja M. Flores, Bernard J. Park, Joseph Dycoco, Anna Arnova, Yael Hirth, Nabil P. Rizk, Manjit Bains, Robert J. Downey, Valerie W. Rusch
Thoracic Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
45. Operative risk of pneumonectomy: Influence of preoperative induction therapy
Henning A. Gaissert, Dong Yoon Keum, Cameron D. Wright, Marek Ancukiewicz, Dean M. Donahue, John C. Wain, Michael Lanuti, Noah C. Choi, Douglas J. Mathisen
MGH, Boston, MA, USA.
Counterpoint: Mark Krasna
Open Discussion |
| 5:00 pm |
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EXECUTIVE SESSION (Members Only)
Ballroom 20 A-C, San Diego Convention Center |
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| TUESDAY AFTERNOON, MAY 13, 2008 |
| 2:00 pm |
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SIMULTANEOUS SCIENTIFIC SESSION – CONGENITAL HEART DISEASE
(8 minutes presentation, 12 minutes discussion)
Room 28 A-C, San Diego Convention Center
Moderators: Charles D. Fraser, James S. Tweddell
46. Surgery for Adults with Congenital Heart Disease Should Be Performed by Congenital Heart Surgeons
Invited Pro: Joseph A. Dearani
Invited Con: Michael A. Acker
Open Discussion
47. Optimal dose of aprotinin for neuroprotection and renal function in a piglet model
Yusuke Iwata, Toru Okamura, David Zurakowski, Richard A. Jonas
Children’s National Heart Institute, Children’s National Medical Center, Washington, DC, USA.
48. Functional health status in an inception cohort of adult survivors with tetralogy of Fallot
Edward J. Hickey, Gruschen Veldtman, Timothy Bradley, Aungkana Gengsakul, Gary Webb, William G. Williams, Cedric Manlhiot, Brian W. McCrindle
The Hospital for Sick Children, Toronto, ON, Canada. |
| 3:10 pm |
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INTERMISSION — VISIT EXHIBITS
Exhibit Hall, San Diego Convention Center |
| 3:45 pm |
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SIMULTANEOUS SCIENTIFIC SESSION — CONGENITAL HEART DISEASEM
Room 28 A-C, San Diego Convention Center
Moderators: Charles D. Fraser, James S. Tweddell
49. Ventricular performance in long-term survivors after Fontan operation
Yuki Nakamura, Toshikatsu Yagihara, Kouji Kagisaki, Ikuo Hagino, Shuichi Shiraishi, Junjiro Kobayashi, Soichiro Kitamura
Cardiothoracic Surgery, National Cardiovascular Center, Suita, Osaka, Japan.
50. How Size Matters: The Complex Relationship Between Pediatric Cardiac Surgical Case Volumes and Mortality Rates in a National Clinical Database
Karl F. Welke1 Sean M. O'Brien2, Eric D. Peterson2, Ross M. Ungerleider1, Marshall L. Jacobs3, Jeffery P. Jacobs4
1. Surgery, Oregon Health and Science University, Portland, OR, USA. 2. Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC, USA. 3. St. Christopher Hospital for Children, Philadelphia, PA, USA. 4. The Congenital Heart Institute of Florida (CHIF), Saint Petersburg and Tampa, FL, USA.
51. What Is the Optimal Timing of Cardiac Transplantation for Failed Fontan: A Single Institution Experience
Ryan R. Davies1, Jonathan Yang1, Robert Sorabella1, Mark Russo1, Ralph S. Mosca1, Jonathan M. Chen2, Jan M. Quagebeur1
1. Columbia University Medical Center, New York, NY, USA. 2. Weill Medical College of Cornell University, New York, NY, USA. |
| 5:00 pm |
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EXECUTIVE SESSION (Members Only)
Ballroom 20 A-C, San Diego Convention Center |
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