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| Impact of Bilateral Versus Single Lung Transplantation on Survival in Recipients 60 Years of Age and Older |
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Back to 86th Annual Meeting Back to Program Outline Objective: Lung Transplant has been increasingly applied for treatment of patients 60 years of age or older. Little is known about outcomes in this age group. More importantly, the procedure of choice, Single (SLT) versus Bilateral (BLT) lung transplantation remains unclear. Therefore, the purpose of this study was to examine short and intermediate outcomes in this age group with particular attention to type of procedure. Methods: All first lung transplant recipients, 60 years of age or older, reported to the United Network for Organ Sharing (UNOS) from 1998 to 2004 were divided into two groups: BLT and SLT. A retrospective review of pertinent baseline characteristics, clinical parameters and outcomes was performed. Kaplan Meier method and Cox proportional hazards regression were used to analyze post-transplant outcomes. Results: A total of 6,785 first lung transplant recipients was listed in the UNOS registry during the study period. Of these, 1656 (24%) recipients were 60 years of age or older (Mean 62.7+2.4 , Median 62, Range 60-87), 364 had BLT and 1292 (78%) had SLT. Using Kaplan Meier Survival analysis, there was no significant difference between the two groups. (Fig.1). Multivariate analysis showed that, BLT versus SLT was not a predictor of mortality. A diagnosis of Idiopathic Pulmonary Fibrosis (IPF) and a donor tobacco history of more than 20 pack years were significantly related to mortality (p <0.001 and p= 0.02 respectively). Conclusions: These findings show no difference in survival of lung transplant recipients 60years of age or older who underwent BLT versus SLT. This data represents the largest report of it's kind in this age group and suggests that recipient and donor characteristics are more important predictors of survival than type of procedure. 
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