| Friday, September 9, 2005 |
| 6:30-8:00 |
Continental Breakfast, Gold Room |
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I. Course Overview
| Moderators: |
Delos M. Cosgrove, III
M.D., Martin B. Leon, M.D. | |
| 8:00-8:15 |
Surgical Advances for Valvular Heart Disease: The "New" Gold Standards
Delos M. Cosgrove,III, M.D. |
| 8:15-8:30 |
The Emergence of Transcatheter Valve Therapies: Clinical Imperatives, Device and Clinical Trial Requirements, and Technology Overview
Martin B. Leon, M.D. |
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II. Aortic Valve Disease - Pathophysiology and Indications for Treatment
| Moderators: |
Robert O. Bonow, M.D.
Sir. Magdi Yacoub | |
| 8:30-8:45 |
"Surgical" Pathology of the Aortic Valve Leaflets
Sir Magdi Yacoub |
| 8:45-9:00 |
Aortic Stenosis as an Active Inflammatory Process: The Role of Medical Therapy
Nalini Rajamannan, M.D. |
| 9:00-9:15 |
The Role of Aortic Root Disease: Implications for Treatment of Aortic Stenosis and Regurgitation
Tirone E. David, M.D. |
| 9:15-9:30 |
When to Operate: Current Guidelines for Medical and Surgical Therapy of Aortic Valve Disease
Robert O. Bonow, M.D. |
| 9:30-9:45 |
Characterizing a "High Risk" Patient Population with Aortic Valve Disease Who Might Benefit from Interventional Therapies
Michael J. Mack, M.D. |
| 9:45-10:00 |
Roundtable Discussion
| Discussants: |
Robert O. Bonow, M.D.
Delos M. Cosgrove, III, M.D.
Sir Magdi Yacoub, M.D. |
Michael J. Mack, M.D.
Nalini Rajamannan, M.D.
Tirone E. David, M.D.
Martin B. Leon, M.D. | |
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III. Edited Taped Case Demonstrations - 1: Aortic Valve Procedures
From: Columbia University Medical Center, The Cleveland Clinic Foundation, and other sites.
| Moderators: |
Donald S. Baim, M.D.
Alain G. Cribier, M.D.
Tirone E. David, M.D.
Eberhard Grube, M.D.
Bruce W. Lytle, M.D.
Ludwig K. von Segesser, M.D. | |
| 10:00-12:00pm |
Minimal Access Valve Surgery
A. Marc Gillinov
Minimally Invasive Aortic Valve Replacement
A. Marc Gillinov
Alternative Aortic Valve Procedures: Aortic Valve Repair and Homograft Aortic Root Replacement
A. Marc Gillinov
Edwards - PVT Balloon-expandable Aortic Valve Bioprosthesis (antegrade approach)
Alain Cribier, M.D.
Corevalve Self-expanding Aortic Valve Bioprotheseis
Eberhard Grube, M.D. |
| 12:00-1:30 |
Lunch, Gold Room/Crystal Room |
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IV. Aortic Valve Disease - Surgical and Interventional Therapies
| Moderators: |
Alain G. Cribier, M.D.
Vaughn A. Starnes, M.D. | |
| 1:30-1:45 |
Minimally Invasive Surgical Approaches for Aortic Valve Disease
Thomislav Mihaljevic, M.D. |
| 1:45-2:00 |
Balloon Aortic Valvuloplasty: Historical Perspectives, Evolving Techniques, and Clinical Indications
Peter Block, M.D. |
| 2:00-2:15 |
Percutaneous Aortic Valve Replacement with the Cribier-Edwards Bioprothesis- The French Experience
Alain G. Cribier, M.D. |
| 2:15-2:30 |
The CoreValve Self-Expanding Bioprosthesis: Design Parameters and Clinical Results
Eberhard Grube, M.D. |
| 2:30-3:15 |
Other Interventional Device Approaches |
| 2:30-2:40 |
Cook Small Intestine Submucosa [SIS] Bileaflet Percutaneous Valve Prosthesis
Carlos E. Ruiz, M.D. |
| 2:40-2:50 |
The Percutaneous AorTx concept for Aortic Valve Replacement
Louis Cannon, M.D. |
| 2:50-3:00 |
Nanotechnology Approaches
Steven R.Bailey, MD |
| 3:00-3:10 |
The Sadra Self-Expanding Percutaneous Aortic Valve Prosthesis
Donald S. Baim, M.D. |
| 3:10-3:20 |
Corazon Aortic Valve Remodeling Concept
Steve Bolling, M.D. |
| 3:20-3:35 |
Roundtable Discussion: Relative Merits and Potential of Lesser-Invasive Surgery and Interventional Approaches for Aortic Valve Disease
| Discussants: |
Donald S. Baim, M.D.
Steven R. Bailey, M.D.
Steven F. Bolling, M.D.
Peter Block, M.D.
Louis Cannon, M.D. |
Eberhard Grube, M.D.
Thomislav Mihaljevic, M.D.
Jeffrey W. Moses, M.D.
Carlos Ruiz, M.D.
Jacques Seguin, M.D. | |
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V. Edited Taped Case Demonstrations - 2: Mitral Valve Procedures
From: Columbia University Medical Center, The Cleveland Clinic Foundation, and other sites.
| Moderators: |
Ottavio R. Alfieri, M.D.
Alain F. Carpentier, M.D.
Ted Feldman, M.D.
Alec Vahanian, M.D.
Gregg W. Stone, M.D.
Hal Wasserman, M.D.
Patrick Whitlow, M.D. | |
| 3:35-5:30 |
Minimally Invasive Mitral Valve Repair with Quadrangular Resection
A. Marc Gillinov
Minimally Invasive Mitral Valve Repair with Sliding Leaflet Technique
A. Marc Gillinov
eValve edge-to-edge repair (case #1)
Patrick Whitlow, M.D.
Cardiac Dimensions Coronary Sinus Annuloplasty
Thilo Tuebler, M.D. |
| 5:30 pm |
Reception In The Exhibition Hall, Imperial Ballroom |
| Saturday, September 10, 2005 |
| 7:00 am |
Continental Breakfast - Exhibition Hall - Imperial Ballroom |
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VI. Mitral Valve Disease - Pathophysiology and Indications for Treatment
| Moderators: |
Allan Schwartz, M.D.
Edward D. Verrier, M.D. | |
| 8:00-8:15 |
Patho-Anatomy and Physiology of Mitral Valve Disease
Carlos G. Duran, M.D. |
| 8:15-8:30 |
When to Operate: Current Guidelines for Medical and Surgical Therapy of Mitral Valve Disease
Allan Schwartz, M.D. |
| 8:30-8:45 |
Are There Changing Clinical Indications for Mitral Valve Procedures?
Blase A. Carabello, M.D. |
| 8:45-9:00 |
Evolving Options for Combined Treatment of Mitral Valve Disease and Atrial Fibrillation
Ralph J. Damiano, Jr., M.D. |
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VII. Edited Taped Case Demonstrations - 3: Mitral Valve Procedures
From: Columbia University Medical Center, The Cleveland Clinic Foundation, and other sites.
| Moderators: |
Donald S. Baim, M.D.
Delos M. Cosgrove, III, M.D.
Carlos G. Duran, M.D.
Peter J. Fitzgerald, M.D.
Craig R. Smith, M.D.
Gregg W. Stone, M.D.
Patrick Whitlow, M.D. | |
| 9:00-11:00 |
Minimal Access Thoracotomy for Mitral Valve Repair
Michael Argenziano
Mitral Valve Anterior Leaflet Repair with Chordal Transfer
A. Marc Gillinov
Edwards-PVT Balloom-expandable Aortic Valve Bioprosthesis (retrograde approach)
John Webb, M.D.
eValve edge-to-edge repair (case #2)
Patrick Whitlow, M.D.
Edwards Viking Coronary Sinus Annuloplasty
John Webb, M.D. |
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VIII. Mitral Valve Disease - Surgical and Interventional Therapies
| Moderators: |
Craig R. Smith, M.D.
Ted Feldman, M.D. | |
| 11:00-11:15 |
Surgical Approaches and Rationale for Mitral Valve Repair Procedures
A. Marc Gillinov, M.D. |
| 11:15-11:45 |
The Surgical "Double Orifice" Procedure for Mitral Regurgitation: Technique and Long-term Results
Ottavio R. Alfieri, M.D. |
| 11:30-11:45 |
Subtleties of Surgical Reduction Ring Annuloplasty: Current Methodologies, and Patient Selection
D. Craig Miller, M.D. |
| 11:45-12:00 |
Minimally Invasive Surgical Approaches for Mitral Valve Disease
W. Randolph Chitwood, Jr., M.D |
| 12:00-1:30 |
Lunch in Exhibition Hall - Imperial Ballroom |
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VIII. Mitral Valve Disease - Surgical and Interventional Therapies (cont.)
| Moderators: |
A. Marc Gillinov, M.D.
Gregg W. Stone, M.D. | |
| 1:30-1:45 |
The eValve Edge-to-Edge Clip Repair: Device Description and Results from the EVEREST Clinical Trial
Ted Feldman, M.D. |
| 1:45-2:00 |
Edwards Milano II Edge-to-Edge Suture Repair
Maurice Buchbinder, M.D. |
| 2:00-2:15 |
Mitralign Transventricular Suture-based Annuloplasty
Donald S. Baim, M.D. |
| 2:15-2:30 |
Myocor Coapsys Transventricular Remodelling: Surgical and Percutaneous Approaches
Todd K. Rosengart, M.D. |
| 2:30-2:45 |
Indirect Coronary Sinus Annuloplasty I: Cardiac Dimensions
 Part 2
Mark Reisman, M.D. |
| 2:45-3:00 |
Indirect Coronary Sinus Annuloplasty II: Edwards Viking
John Webb, M.D. |
| 3:00-3:10 |
Indirect Coronary Sinus Annuloplasty III: ViaCor- Animal Experimental Results
Motoya Hayase, M.D. |
| 3:10-3:20 |
Indirect Coronary Sinus Annuloplasty III: Viacor- Devices Design and Early Intra Operative Clinical Experiences
Stephen Ellis, M.D. |
| 3:20-4:00 |
Other Interventional Device Approaches |
| 3:20-3:30 |
The Mitral Solutions Approach to Interventional and Minimally Invasive Surgical Treatment of Mitral Regurgitation
Peter Fitzgerald, M.D. |
| 3:30-3:40 |
The Ample Percutaneous Septal Sinus Shortening Concept (PS3 System): A Novel Procedure for the Treatment of Functional Mitral Regurgitation
Jason H, Rogers, M.D. |
| 3:40-3:50 |
The QuantumCor Transventricular Annulus Remodeling Concept: Device Design and Experimental Results
Richard Heuser, M.D. |
| 3:50-4:05 |
The Emerging Problem of Managing Complications from Unsuccessful Transcatheter Valve Therapy
Michael Argenziano, M.D |
| 4:05-4:30 |
Roundtable Discussion: Relative Merits and Potential of Lesser-Invasive Surgery and Interventional Approaches for Mitral Valve Disease
| Discussants: |
Michael Argenziano, M.D.
Maurice Buchbinder, M.D.
Motoya Hayase, M.D.
Ted Feldman, M.D. |
Mark Reisman, M.D.
Todd K. Rosengart, M.D.
Gregg W. Stone, M.D. | |
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IX. Innovative Surgical and Interventional Procedures for Pulmonary and Tricuspid Valve Disease and Other Congenital Heart Diseases
| Moderators: |
Phillip Bonhoeffer, M.D.
Edward L. Bove, M.D. | |
| 4:30-4:45 |
Important Pathophysiologic Considerations for Right-Sided Valve and Congenital Anomalies
Frank L. Hanley, M.D. |
| 4:45-5:00 |
Current Surgical and Interventional Treatment Approaches for Right-Sided Valve and Congenital Anomalies
Marc R. de Leval, M.D. |
| 5:00-5:15 |
Clinical Experiences with Transcatheter Pulmonary Valve and Right-Sided Valve Conduit Replacement
Phillip Bonhoeffer, M.D. |
| 5:15-5:30 |
Panel Discussion: Lesser-Invasive Approaches to the Treatment of Congenital Heart Disease
| Discussants: |
Edward L. Bove, M.D.
Marc de Leval, M.D.
Phillip Bonhoeffer, M.D.
Frank L. Hanley, M.D. | |
| 5:30 pm |
Adjourn |
| Sunday, September 11, 2005 |
| 7:00 am |
Continental Breakfast - Exhibition Hall - Imperial Ballroom |
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X. Clinical Trial Design and FDA Regulatory Issues
| Moderators: |
Bram Zuckerman, M.D.
Craig R. Smith, M.D. | |
| 8:00-8:20 |
A"Primer" on Clinical Trial Design: Implications for Transcatheter Valve Therapies
Richard E. Kuntz, M.D.
FDA Regulatory Considerations |
| 8:20-8:40 |
FDA Regulatory Considerations for Transcatheter Valve Therapies: Device Testing Standards, Pre-Clinical Studies and Clinical Trial Requirements
Julie A. Swain, M.D.
Bram Zuckerman, M.D. |
| 8:40-9:00 |
Reflections on Surgical Mitral Valve Repair: Current Status and Future Directions
Alain F. Carpentier, M.D. |
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XI. Controversies in Valvular Heart Disease Therapeutics: Debates and Discussions
(10 mins protagonist 10 mins antagonist, 10 mins discussion)
| Moderators: |
Blasé A. Carabello, M.D.
Delos M. Cosgrove, III, M.D. | |
| 9:00-9:30 |
The Presence of Significant Mitral Regurgitation Alone Should Justify Surgical or Interventional treatment
Pro: Hartzell V. Schaff, M.D.
Con: Robert O. Bonow, M.D. |
| 9:30-10:00 |
The Regulatory Approval Pathway for New Interventional Valve Therapies Requires Randomized Clinical Trials vs. The Surgical "Gold Standard"
Pro: Vaughn A. Starnes, M.D.
Con: Martin B. Leon, M.D. |
| 10:00-10:30 |
Morning Break in Exhibition Hall |
| 10:30-11:00 |
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Interventional Aortic Valve Implantation for Aortic Stenosis is Unnecessary and Dangerous
Pro: Lawrence H. Cohn, M.D.
Con: Jeffrey W. Moses, M.D |
| 11:00-11:30 |
Minimally Invasive Valve Procedures are Becoming the New Surgical Standard-of-Care
Pro: W. Randolph Chitwood, Jr. M.D.
Con: Irving L. Kron, M.D. |
| 11:30 am |
Adjourn |
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